Dual role of Ski in pancreatic cancer cells: tumor-promoting versus metastasis-suppressive function
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چکیده
منابع مشابه
Tumor-suppressive and promoting function of transforming growth factor beta.
Transforming growth factor beta (TGFbeta) is a multifunctional polypeptide. Its role in carcinogenesis can be either suppressive or promoting depending on tumor developmental stages and cellular context. During the early phase of epithelial tumorigenesis, TGFbeta inhibits primary tumor development and growth by inducing cell cycle arrest and possibly apoptosis. However, in late stages of progre...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2009
ISSN: 1460-2180,0143-3334
DOI: 10.1093/carcin/bgp154